@Breffni-Potter Example file was created December 30, 2014. Created in Excel 2010 and being edited in 2010. We do have different files that were created in different version but all excel files this applies to.
The weird thing is if I give full access permissions there is no problem. I hope that gives you insight.
UPDATE: Scatch that. Still an issue. It's only here and there. Sometimes she can leave the file open and itll save ten times in a row and then it won't.