For any semblance of keeping data from the NSA you need to air gap your data from US soil and US staff. You need to ensure that no American can be pressured to hack and steal data out of the country it is in. That's a starting point.
The NSA are agents if some foreign power, I swear, with a mandate to force big business out of the US. The NSA are one of the greatest threats our generation will face. Openly foreign agents have no means to be as damaging to the American people as these guys.