Does the same principle apply if I made the default disk 4 or 6TB in size?
That is really just up to how you want to manage it.
At that scale, I would personally want it to be a separate virtual disk. But that is honestly only because I have more options for recovery. It is easier to work with a disk that you know have nothing but data than tryign to attach a once bootable disk to a new VM, etc.
None of that has anything to do with the host and how it mounts the space.
Thanks, that's kinda what I thought, just wanted to make sure.