My prescription lenses have some kind of coating on it that is supposed to block the "harmful blue light rays," but I've never tried the yellow tinted glasses. I can definitely see a difference looking at my monitor through my lenses vs. naked eyes. I would say for the better.
My opinion could be skewed by the fact that I've needed prescription glasses for a while now and finally just got them. My eyes feel so much better when I'm going to sleep. Way less fatigued.